Professor. Olarinde Stephen Adewole

Area of Specialization/Research interest:   Endocrinology Immunohistochemistry Transmission Electron Microscopy

E-mail address: stephenadewole@yahoo.co.uk

Tel: +234(0)8034074930

I contributed effectively, in various capacities, to the academic, social and general growth of the Department of Anatomy and Cell Biology, University and the community at large. I developed research projects in the areas of experimentally-induced diabetes mellitus in laboratory animals. I have initiated collaborations between my department and Optics and Imaging Centre, Doris Duke Medical Research institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa after my Post-Doctoral Fellowship Programmes in South Africa in 2006. This collaboration emanated in the signing of Memorandom of Understanding (MoU) between Obafemi Awolowo University and University of KwaZulu-Natal, Durban, South Africa

My research focus has been in markers of oxidative stress evaluating the ameliorative effects of plant extracts and drugs on stressful tissues. Oxidative stress have been implicated in the etiology of numerous common diseases especially diabetes mellitus. As Anatomist, the use of electron microscopy, histological, histochemical, and immunohistochemical techniques have given us better understanding of pathogenicity of diabetes mellitus and its effects on the microanatomy of various organs in the body and we are able to monitor the ameliorative effects of these herbal products administered. The study of direct effect of chronic hyperglycemia on pro-oxidant and antioxidant  biomolecules such as MDA, ROS, NO,   MnSOD, GSH-Px, H₂O₂, GSH/GSSG, Mitochondrial complex II, III, IV, and V, carbonyls and thiols have broaden our knowledge of pathology of diabetes mellitus.

My laboratory currently focuses on the enrichment of mitochondria antioxidants, consequently, therapeutic strategies to decrease ROS production.